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Description

A decrease in cerebral glutathione has been observed in brain tissue undergoing oxidative stress both in aging and neurodegeneration

When chronic inflammation is part of the research interest, KLOW is the more common choice

It is not currently FDA-approved for any specific adult indication

Mechanistically, luteolin imposes strong cell cycle regulation by downregulating cyclin E1 (CCNE1) and its catalytic partners CDK2 and CDK4, thereby inducing G1/S phase arrest and preventing DNA replication licensing